Sibutramina

Sibutramina, ou Cloridrato de Sibutramina monoidratado, é indicado para o tratamento de obesidade. Sua venda é controlada com retenção de receita. Deve se ter muita cautela ao utilizar esta droga, pois há efeitos colaterais indesejados e a redução do apetite pode causar graves consequências se não houver um acompanhamento médico adequado.

Sibutramina é inibidor de reabsorção de neurotransmissores, o que ajuda a elevar a saciedade ao inibir a reabsorção da serotonina em 73%), norepinefrina (em 54%) e dopamina (em 16%). Sibutramina foi aprovada pelo FDA (órgão norte-americano que regula medicamentos) como remédio para emagrecer para tratamento da obesidade em Novembro de 1997.

Os efeitos colaterais mais comuns durante o uso de sibutramina são taquiarritmia, pele seca, boca seca, constipação, dor de cabeça, náuseas, mal humor, desânimo e irritabilidade.

Alguns efeitos adversos podem ser muito sérios, como Trombocitopenia, Síndrome de Serotonina e intervalo QT prolongado. Então resista a tentação de comprar o medicamento sem receita e/ou subornar o farmacêutico.

Como funciona a Sibutramina

A Sibutramina age em duas partes do sistema nervoso central: no centro do apetite e no da saciedade. Ambos estão localizados na região do hipotálamo.

Sibutramina

Sibutramina

A droga reduz a recaptação do neurotransmissor responsável pelo apetite (noradrenalina) e do que causa a sensação de saciedade (serotonina). Isso impede que os neurotransmissores entrem nos neurônios. A pessoa fica com menos apetite e sente mais saciedade porque os neurônios estão banhados de noradrenalina e serotonina.

Vale lembrar que há contra-indicações no uso de sibutramina quando há uso associado de outros medicamentos anorexígenos, descongestionantes, sedativos da tosse, ergotamina e derivados, lítio, pessoas com antecedentes de transtornos alimentares como anorexia ou bulimia, glaucoma, hipertensão arterial (ou histórico),  convulsões (ou histórico), doença cardíaca (ou histórico), doença ou dano cerebral, derrame, cálculos nas vias biliares (ou histórico), patologias renais severas e patologias hepáticas severas.

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  780. Posted by Denise
  781. Posted by Vanessa
  782. Posted by geovana
  783. Posted by viviane
  784. Posted by Ju
  785. Posted by Josiane
  786. Posted by Jéssica C. da Silva
  787. Posted by antonieta
  788. Posted by gildete dias almeida
  789. Posted by camila
  790. Posted by camila
  791. Posted by clau
  792. Posted by bruna de lourdes manteiro
  793. Posted by viviane mendes
  794. Posted by Vani Cristina
  795. Posted by kamila sales
  796. Posted by Cah
  797. Posted by rafaela
  798. Posted by GEYSE SILVA
  799. Posted by tycii
  800. Posted by Geyse Silva
  801. Posted by fran
  802. Posted by Ju
  803. Posted by Márcia
  804. Posted by Lilian
  805. Posted by Maria
  806. Posted by Lilian
  807. Posted by Lilian
  808. Posted by Mavi
  809. Posted by Mavi
  810. Posted by rosicleide
  811. Posted by Dejane Munari
  812. Posted by TEREZA LOPES
  813. Posted by Cátia Guerreiro

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